ATP 250 · 2021-10-18 · draw of 32
Moscow 2021
HardFinal
| 🇷🇺 Aslan Karatsev | d. | 🇭🇷 Marin Cilic | 6-2 6-4 | H2H |
Semifinals
| 🇭🇷 Marin Cilic | d. | 🇱🇹 Ricardas Berankis | 6-3 6-4 | H2H |
| 🇷🇺 Aslan Karatsev | d. | 🇷🇺 Karen Khachanov | 7-6(7) 6-1 | H2H |
Quarterfinals
| 🇱🇹 Ricardas Berankis | d. | 🇫🇷 Adrian Mannarino | 6-2 7-6(1) | H2H |
| 🇭🇷 Marin Cilic | d. | 🇪🇸 Pedro Martinez | 6-1 6-2 | H2H |
| 🇷🇺 Karen Khachanov | d. | 🇦🇺 John Millman | 7-5 7-6(4) | H2H |
| 🇷🇺 Aslan Karatsev | d. | 🇫🇷 Gilles Simon | 6-4 6-3 | H2H |
Round of 16
| 🇫🇷 Adrian Mannarino | d. | 🇷🇺 Andrey Rublev | 5-7 7-6(4) 6-3 | H2H |
| 🇱🇹 Ricardas Berankis | d. | 🇦🇷 Federico Coria | 6-2 6-1 | H2H |
| 🇪🇸 Pedro Martinez | d. | 🇷🇸 Filip Krajinovic | 6-3 6-4 | H2H |
| 🇭🇷 Marin Cilic | d. | 🇺🇸 Tommy Paul | 7-5 6-3 | H2H |
| 🇦🇺 John Millman | d. | 🇺🇦 Illya Marchenko | 6-1 5-7 6-4 | H2H |
| 🇷🇺 Karen Khachanov | d. | 🇦🇺 James Duckworth | 3-6 6-3 6-1 | H2H |
| 🇫🇷 Gilles Simon | d. | 🇺🇸 Mackenzie McDonald | 6-3 6-2 | H2H |
| 🇷🇺 Aslan Karatsev | d. | 🇧🇾 Egor Gerasimov | 6-4 6-3 | H2H |
Round of 32
| 🇫🇷 Adrian Mannarino | d. | 🇷🇺 Roman Safiullin | 1-6 7-6(6) 6-4 | H2H |
| 🇦🇷 Federico Coria | d. | 🇷🇺 Alibek Kachmazov | 6-2 5-7 6-2 | H2H |
| 🇱🇹 Ricardas Berankis | d. | 🇷🇺 Evgeny Donskoy | 6-1 6-3 | H2H |
| 🇪🇸 Pedro Martinez | d. | 🇦🇷 Guido Pella | 6-2 RET | H2H |
| 🇺🇸 Tommy Paul | d. | 🇸🇪 Mikael Ymer | 7-6(7) 7-5 | H2H |
| 🇭🇷 Marin Cilic | d. | 🇧🇦 Damir Dzumhur | 6-7(4) 6-1 6-1 | H2H |
| 🇺🇦 Illya Marchenko | d. | 🇰🇿 Alexander Bublik | 6-4 6-3 | H2H |
| 🇦🇺 John Millman | d. | 🇫🇷 Benjamin Bonzi | 6-7(5) 6-4 6-3 | H2H |
| 🇦🇺 James Duckworth | d. | 🇭🇷 Borna Gojo | 3-6 7-5 6-2 | H2H |
| 🇫🇷 Gilles Simon | d. | 🇷🇸 Laslo Djere | 6-7(3) 7-5 6-3 | H2H |
| 🇺🇸 Mackenzie McDonald | d. | 🇯🇵 Yoshihito Nishioka | 6-3 6-4 | H2H |
| 🇧🇾 Egor Gerasimov | d. | 🇷🇸 Miomir Kecmanovic | 6-3 1-6 6-4 | H2H |