ATP 250 · 2021-05-17 · draw of 32
Lyon 2021
ClayFinal
| 🇬🇷 Stefanos Tsitsipas | d. | 🇬🇧 Cameron Norrie | 6-3 6-3 | H2H |
Semifinals
| 🇬🇷 Stefanos Tsitsipas | d. | 🇮🇹 Lorenzo Musetti | 4-6 6-3 6-0 | H2H |
| 🇬🇧 Cameron Norrie | d. | 🇷🇺 Karen Khachanov | 6-1 6-1 | H2H |
Quarterfinals
| 🇬🇷 Stefanos Tsitsipas | d. | 🇯🇵 Yoshihito Nishioka | 6-3 6-4 | H2H |
| 🇮🇹 Lorenzo Musetti | d. | 🇸🇮 Aljaz Bedene | 6-3 7-6(2) | H2H |
| 🇷🇺 Karen Khachanov | d. | 🇫🇷 Richard Gasquet | 6-1 7-6(3) | H2H |
| 🇬🇧 Cameron Norrie | d. | 🇫🇷 Arthur Rinderknech | 6-3 3-6 6-3 | H2H |
Round of 16
| 🇬🇷 Stefanos Tsitsipas | d. | 🇺🇸 Tommy Paul | 6-1 6-4 | H2H |
| 🇯🇵 Yoshihito Nishioka | d. | 🇫🇷 Gael Monfils | 4-6 6-3 7-6(2) | H2H |
| 🇸🇮 Aljaz Bedene | d. | 🇧🇪 David Goffin | 7-6(4) 6-3 | H2H |
| 🇮🇹 Lorenzo Musetti | d. | 🇺🇸 Sebastian Korda | 6-3 1-6 6-4 | H2H |
| 🇷🇺 Karen Khachanov | d. | 🇵🇱 Kamil Majchrzak | 7-6(4) 6-3 | H2H |
| 🇫🇷 Richard Gasquet | d. | 🇦🇷 Diego Schwartzman | 6-3 7-5 | H2H |
| 🇫🇷 Arthur Rinderknech | d. | 🇮🇹 Jannik Sinner | 6-7(7) 6-2 7-5 | H2H |
| 🇬🇧 Cameron Norrie | d. | 🇦🇹 Dominic Thiem | 6-3 6-2 | H2H |
Round of 32
| 🇺🇸 Tommy Paul | d. | 🇫🇷 Jo-Wilfried Tsonga | 6-3 6-3 | H2H |
| 🇯🇵 Yoshihito Nishioka | d. | 🇫🇷 Ugo Humbert | 3-6 6-3 6-4 | H2H |
| 🇫🇷 Gael Monfils | d. | 🇧🇷 Thiago Seyboth Wild | 7-5 6-4 | H2H |
| 🇸🇮 Aljaz Bedene | d. | 🇫🇷 Gilles Simon | 6-2 6-3 | H2H |
| 🇺🇸 Sebastian Korda | d. | 🇫🇷 Pierre-Hugues Herbert | 7-6(5) 6-4 | H2H |
| 🇮🇹 Lorenzo Musetti | d. | 🇨🇦 Felix Auger-Aliassime | 7-6(3) 3-6 7-5 | H2H |
| 🇷🇺 Karen Khachanov | d. | 🇫🇷 Benjamin Bonzi | 6-1 4-6 7-6(4) | H2H |
| 🇵🇱 Kamil Majchrzak | d. | 🇵🇹 Joao Sousa | 6-3 7-6(8) | H2H |
| 🇫🇷 Richard Gasquet | d. | 🇫🇷 Gregoire Barrere | 5-7 6-4 6-3 | H2H |
| 🇮🇹 Jannik Sinner | d. | 🇷🇺 Aslan Karatsev | 0-6 6-3 6-4 | H2H |
| 🇫🇷 Arthur Rinderknech | d. | 🇸🇪 Mikael Ymer | 6-3 6-7(4) 6-2 | H2H |
| 🇬🇧 Cameron Norrie | d. | 🇫🇷 Corentin Moutet | 7-5 6-3 | H2H |